Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879542 | 0.87 | KDM4E (0.45) | KDM4ECYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL7868474 | 0.82 | CYP2C9 (0.40) | CYP2C19LMNACPB2TDP1 | |
| Hydrochloric Acid SCHEMBL7873720 | 0.81 | TDP1 (0.41) | CYP2C19LMNACPB2TDP1 | |
| SCHEMBL7875247 | 0.73 | ESRRG (0.42) | KMT2AMAPTALDH1A1 | |
| SCHEMBL8444492 | 0.73 | QPCTL (0.37) | KDM4ECYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL8443854 | 0.73 | KCNH2 (0.44) | CYP2D6CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8447347 | 0.72 | KCNH2 (0.43) | CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL7876986 | 0.71 | ALDH1A1 (0.41) | KDM4ELMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL4910266 | 0.69 | MAPT (0.48) | KDM4ECYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL8445998 | 0.68 | QPCTL (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |