Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863552 | 0.87 | ALDH1A1 (0.34) | SMN1; SMN2KDM4EL3MBTL1MAPTHPGD | |
| SCHEMBL8443188 | 0.84 | PTGER4 (0.33) | SMN1; SMN2KDM4ETDP1L3MBTL1HIF1A | |
| SCHEMBL7498420 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL7130516 | 0.84 | HIF1A (0.42) | SMN1; SMN2KDM4EL3MBTL1MAPTNPC1 | |
| SCHEMBL7742072 | 0.83 | ATM (0.37) | TDP1L3MBTL1MAPTHIF1ALMNA | |
| SCHEMBL8030454 | 0.83 | L3MBTL1 (0.37) | SMN1; SMN2KDM4ETDP1L3MBTL1NPC1 | |
| SCHEMBL7744894 | 0.83 | MAOA (0.32) | SMN1; SMN2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7744876 | 0.83 | MAPT (0.35) | SMN1; SMN2KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL8440483 | 0.81 | KDM4E (0.32) | SMN1; SMN2KDM4ETDP1L3MBTL1HIF1A | |
| SCHEMBL7742973 | 0.81 | NPC1 (0.39) | SMN1; SMN2KDM4ETDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313344-B1 | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-06 | — | — | US | disclosed |