Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704838 | 0.84 | ALDH1A1 (0.67) | KMT2AALDH1A1HTTNPSR1LMNA | |
| SCHEMBL7868867 | 0.82 | ALDH1A1 (0.65) | KMT2AALDH1A1HTTNPSR1LMNA | |
| SCHEMBL7866978 | 0.77 | KMT2A (0.60) | KMT2AALDH1A1HTTNPSR1LMNA | |
| SCHEMBL7862238 | 0.76 | ALDH1A1 (0.56) | KMT2AALDH1A1HTTNPSR1LMNA | |
| SCHEMBL24785864 | 0.75 | NR3C2 (0.46) | ALDH1A1LMNAMAPT | |
| SCHEMBL7868839 | 0.75 | HTT (0.63) | KMT2AALDH1A1HTTNPSR1LMNA | |
| SCHEMBL19066564 | 0.75 | ALDH1A1 (0.69) | KMT2AALDH1A1HTTNPSR1LMNA | |
| SCHEMBL7862237 | 0.74 | KMT2A (0.57) | KMT2AALDH1A1HTTNPSR1LMNA | |
| SCHEMBL8448862 | 0.74 | TDP1 (0.57) | ALDH1A1HTTNPSR1KDM4EGAA | |
| SCHEMBL5189622 | 0.73 | ALDH1A1 (0.67) | KMT2AALDH1A1HTTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |