Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870900 | 0.86 | KMT2A (0.66) | ALDH1A1GAAKMT2ALMNAPOLB | |
| SCHEMBL7870908 | 0.83 | ALDH1A1 (0.62) | ALDH1A1GAAKMT2AMMP1MEN1 | |
| SCHEMBL7874010 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL7870795 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAAKMT2AMMP1MEN1 | |
| SCHEMBL7874061 | 0.79 | ALDH1A1 (0.58) | ALDH1A1GAAKMT2AMMP1MEN1 | |
| SCHEMBL1940753 | 0.75 | HSD11B1 (0.63) | ALDH1A1GAAKMT2AMMP1MEN1 | |
| SCHEMBL1940052 | 0.75 | KMT2A (0.59) | ALDH1A1GAAKMT2AMMP1MEN1 | |
| SCHEMBL7862148 | 0.75 | KMT2A (0.62) | ALDH1A1GAAKMT2AMMP1MEN1 | |
| SCHEMBL8415589 | 0.74 | KMT2A (0.59) | ALDH1A1GAAKMT2AMMP1MEN1 | |
| SCHEMBL24333929 | 0.74 | ALDH1A1 (0.49) | ALDH1A1GAAKMT2AMMP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |