Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874157 | 0.85 | KMT2A (0.71) | ALDH1A1GAAKMT2ALMNAPOLB | |
| SCHEMBL7870795 | 0.84 | ALDH1A1 (0.71) | ALDH1A1GAAKMT2AMEN1MMP1 | |
| SCHEMBL28897130 | 0.83 | KMT2A (0.53) | ALDH1A1GAAKMT2AMEN1MMP1 | |
| SCHEMBL7874047 | 0.83 | KMT2A (0.53) | ALDH1A1GAAKMT2AMEN1MMP1 | |
| SCHEMBL7874068 | 0.83 | POLB (0.59) | ALDH1A1KMT2AMEN1MMP1LMNA | |
| SCHEMBL1346520 | 0.83 | ALDH1A1 (0.65) | ALDH1A1GAAKMT2AMEN1MMP1 | |
| SCHEMBL28101227 | 0.83 | MAPT (0.59) | KMT2AMMP1LMNAHTTHSD11B1 | |
| SCHEMBL7868841 | 0.83 | ALDH1A1 (0.58) | ALDH1A1GAAKMT2AMEN1MMP1 | |
| SCHEMBL7874061 | 0.83 | ALDH1A1 (0.58) | ALDH1A1GAAKMT2AMEN1MMP1 | |
| SCHEMBL16144557 | 0.82 | KMT2A (0.57) | ALDH1A1GAAKMT2AMEN1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |