Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | GRK2 | P25098 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868860 | 0.84 | TXNRD1 (0.54) | KMT2APKMPOLBMEN1APAF1 | |
| SCHEMBL7870900 | 0.82 | KMT2A (0.66) | ALDH1A1KMT2APOLBMAPK1GAA | |
| SCHEMBL7868841 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2APOLBMAPK1MEN1 | |
| SCHEMBL10434033 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTBCL9CTNNB1 | |
| SCHEMBL7861808 | 0.77 | HTT (0.57) | ALDH1A1KMT2APKMPOLBMAPT | |
| SCHEMBL27523212 | 0.77 | GSK3B (0.51) | ALDH1A1KMT2APKMMAPK1MEN1 | |
| SCHEMBL19126866 | 0.75 | CA2 (0.59) | ALDH1A1KMT2APKMHSD11B1 | |
| SCHEMBL2775897 | 0.74 | KMT2A (0.59) | ALDH1A1KMT2APKMMAPK1MEN1 | |
| SCHEMBL14816982 | 0.72 | PKM (0.49) | ALDH1A1KMT2APKMPOLBMAPK1 | |
| SCHEMBL8770176 | 0.72 | KMT2A (0.62) | ALDH1A1KMT2APKMPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |