Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 14/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869024 | 0.92 | ALDH1A1 (0.56) | ALDH1A1CYP19A1NAMPT | |
| SCHEMBL7869029 | 0.86 | SCD (0.41) | ALDH1A1NAMPT | |
| SCHEMBL8494125 | 0.86 | SCD (0.43) | NAMPT | |
| SCHEMBL7872872 | 0.84 | SCD (0.42) | NAMPT | |
| SCHEMBL7866466 | 0.81 | TTK (0.42) | ALDH1A1 | |
| SCHEMBL7861548 | 0.81 | HCAR3 (0.46) | ALDH1A1 | |
| SCHEMBL7869108 | 0.81 | PRMT5 (0.46) | NAMPT | |
| SCHEMBL7873078 | 0.80 | PLA2G1B (0.45) | ALDH1A1 | |
| SCHEMBL7873013 | 0.79 | PRMT5 (0.47) | ALDH1A1NAMPT | |
| SCHEMBL7868103 | 0.78 | ADRA2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |