Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870341 | 0.96 | CA2 (0.43) | CA2EGFRNPC1RAB9AALDH1A1 | |
| SCHEMBL7869130 | 0.90 | KMT2A (0.44) | CA2L3MBTL1EGFRNPC1RAB9A | |
| SCHEMBL7862795 | 0.89 | EGFR (0.44) | CA2EGFRP4HTM | |
| SCHEMBL7871727 | 0.88 | CA2 (0.44) | CA2EGFRNPC1RAB9AALDH1A1 | |
| SCHEMBL7871605 | 0.88 | HSP90AA1 (0.44) | NPC1RAB9AMLYCDKMT2AMEN1 | |
| SCHEMBL7871629 | 0.88 | CA2 (0.46) | CA2L3MBTL1EGFRNPC1RAB9A | |
| SCHEMBL7867899 | 0.87 | SMN1; SMN2 (0.43) | CA2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL7869436 | 0.87 | NPC1 (0.44) | NPC1RAB9AMLYCDSMN1; SMN2P4HTM | |
| SCHEMBL7867792 | 0.86 | CA2 (0.49) | CA2L3MBTL1NAAAEGFRMLYCD | |
| SCHEMBL7862801 | 0.86 | CA2 (0.48) | CA2L3MBTL1NAAAEGFRMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |