Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871449 | 0.88 | GSR (0.42) | ALOX15ELANEHPGDHSD17B10 | |
| SCHEMBL7869540 | 0.87 | MEN1 (0.46) | ATMKMT2AMEN1TP53ROCK2 | |
| SCHEMBL9333280 | 0.87 | ALOX15 (0.62) | ALOX15ATMKMT2AMEN1THRB | |
| SCHEMBL9335752 | 0.81 | HSD17B10 (0.61) | ALOX15KMT2AMEN1THRBHSD17B10 | |
| SCHEMBL9384000 | 0.80 | POLB (0.38) | KMT2AMEN1TP53 | |
| SCHEMBL8329396 | 0.78 | MEN1 (0.46) | KMT2AMEN1THRBROCK2HSD17B10 | |
| SCHEMBL9726878 | 0.77 | MAPK1 (0.52) | ALOX15TP53HSD17B10 | |
| SCHEMBL9332729 | 0.76 | MEN1 (0.46) | KMT2AMEN1TP53 | |
| SCHEMBL7873335 | 0.76 | CRBN (0.41) | KMT2AMEN1HPGD | |
| SCHEMBL9727194 | 0.75 | TP53 (0.46) | KMT2AMEN1TP53ROCK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1055672-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 2000-11-29 | — | — | EP | disclosed |