SCHEMBL7869586

SCHEMBL7869586

C=Cc1ccc([Si](C)(C)Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.40
HDAC8 Q9BY41 3/20 0.39
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7649599 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL23493481 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL141101 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL27193611 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL706038 0.79 ESR1 (0.32)
SCHEMBL899595 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL8758099 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL9488658 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL15473032 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL30423535 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-4134382-B1 HYDROGENATED CONJUGATED DIENE-BASED POLYMER, HYDROGENATED CONJUGATED DIENE-BASED POLYMER COMPOSITION, RUBBER COMPOSITION, AND METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE-BASED POLYMER ASAHI CHEMICAL IND (JP) 2025-05-07 EP disclosed
CN-119497723-A Conjugated diene polymer, molded article, method for producing conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2025-02-21 CN disclosed
CN-119462990-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2025-02-18 CN disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-12215179-B2 Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, oil extended conjugated diene-based polymer, rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
US-20240425702-A1 Block Copolymer, Asphalt Composition, and Modified Asphalt Mixture ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-26 US disclosed
CN-114341206-B Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2024-12-20 CN disclosed
CN-115298225-B Hydrogenated conjugated diene polymer, hydrogenated conjugated diene polymer composition, rubber composition, and method for producing hydrogenated conjugated diene polymer 旭化成株式会社 2024-12-13 CN disclosed
US-5210143-A Block polymer of nonelastic vinyl aromatic segments. elastic diene segments and a vinyl aromatic compound having halo- or oxysilyl groups or metal halide or oxymetal groups; pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-11 US disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0505997-A2 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
US-5115034-A Branching polymers with organometallic styrene derivative, a hydrocarbyl lithium initiator and a monomer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-05-19 US disclosed
US-5079090-A Pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-07 US disclosed
US-4996266-A Branched elastomeric and block copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-26 US disclosed
US-4906691-A Adhesive compositions made with condensed phase polymers and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-06 US disclosed
US-4857618-A ELASTOMERIC, ANIONIC COPOLYMERS; ORGANOMETALLIC CONDENSING AGENT; PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed
US-4857615-A Method of making condensed phase polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 ALDH1A1 2948/4885TSHR 159/4885HDAC8 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.