Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870492 | 0.99 | NPC1 (0.52) | NPC1RAB9AHPGDTSHRALDH1A1 | |
| SCHEMBL17203727 | 0.75 | TP53 (0.74) | TSHRGAAL3MBTL1TP53PLA2G4B | |
| SCHEMBL6419717 | 0.75 | ALDH1A1 (0.59) | NPC1RAB9AHPGDTSHRALDH1A1 | |
| SCHEMBL6547083 | 0.75 | PLA2G4A (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28063453 | 0.74 | KCNH2 (0.58) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL1896293 | 0.74 | ALDH1A1 (0.57) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL533825 | 0.73 | TP53 (0.77) | TSHRGAAL3MBTL1TP53PLA2G4B | |
| SCHEMBL6705357 | 0.73 | TP53 (0.77) | TSHRGAAL3MBTL1TP53PLA2G4B | |
| SCHEMBL18302060 | 0.73 | TP53 (0.77) | TSHRGAAL3MBTL1TP53PLA2G4B | |
| SCHEMBL1623628 | 0.73 | TP53 (0.77) | TSHRGAAL3MBTL1TP53PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6312811-B1 | Photochromic naphtho [2,1-b]pyran compounds containing bithienyl or terthienyl substituents, process for their manufacture, and photochromic materials and articles obtained | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-11-06 | — | — | US | disclosed |