SCHEMBL786994

SCHEMBL786994

Cc1cc(C)c(-c2ccc3sc4c(-c5ccc6[nH]c7ccccc7c6c5)cc(-c5c(C)cc(C)cc5C)cc4c3c2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.37
KMT2A Q03164 4/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 3/20 0.35
RAB9A P51151 2/20 0.35
KDM4E B2RXH2 3/20 0.35
ATM Q13315 1/20 0.35
AHR P35869 1/20 0.35
PIM1 P11309 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
HPGD P15428 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ABCB1 P08183 1/20 0.34
CTSV O60911 1/20 0.34
CTSL P07711 1/20 0.34
TNKS O95271 2/20 0.34
TNKS2 Q9H2K2 2/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788554 0.94 PIM1 (0.33) KMT2AMEN1RAB9AKDM4EPIM1
SCHEMBL787124 0.87 KIF11 (0.42) KIF11KMT2AMAPTMEN1RAB9A
SCHEMBL10227106 0.86 KIF11 (0.47) KIF11KMT2AMAPTMEN1RAB9A
SCHEMBL10226925 0.84 ALOX5 (0.51) KMT2AMAPTMEN1RAB9APIM1
SCHEMBL10227377 0.81 LIMK1 (0.40) KIF11KMT2AMAPTMEN1RAB9A
SCHEMBL10227353 0.81 LIMK1 (0.40) KIF11KMT2AMAPTMEN1RAB9A
SCHEMBL4549335 0.81 CYP1A2 (0.37) KMT2AMAPTMEN1RAB9AATM
SCHEMBL10227371 0.80 RAB9A (0.35) KIF11KMT2AMEN1RAB9AKDM4E
SCHEMBL10227360 0.80 ALOX5 (0.40) KIF11KMT2AMAPTMEN1RAB9A
SCHEMBL10227350 0.80 HTR2B (0.41) KIF11KMT2AMAPTMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 KIF11 1085/4885KMT2A 1914/4885MAPT 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.