SCHEMBL7870106

SCHEMBL7870106

N#Cc1c(F)c(F)c(Oc2ccc(Cl)cc2Cl)c(F)c1C#N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.43
SLC6A4 P31645 2/20 0.43
KCNH2 Q12809 1/20 0.43
TTR P02766 4/20 0.42
SLC6A2 P23975 2/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
PGR P06401 1/20 0.42
HSP90AA1 P07900 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
MAPT P10636 1/20 0.42
HSPA5 P11021 1/20 0.42
HPGD P15428 1/20 0.42
CBR1 P16152 1/20 0.42
TBXA2R P21731 1/20 0.42
AGTR1 P30556 1/20 0.42
MRGPRX4 Q96LA9 3/20 0.39
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
PGGT1B P53609 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7868377 0.81 MAPT (0.43) SLC6A3SLC6A4SLC6A2LMNAMAPT
SCHEMBL2451304 0.81 SLC22A12 (0.38) SLC6A3SLC6A4KCNH2LMNAMRGPRX4
SCHEMBL7873493 0.78 L3MBTL1 (0.42) SLC6A4KCNH2LMNAMAPTHPGD
SCHEMBL11760295 0.74 MRGPRX4 (0.48) SLC6A3SLC6A4KCNH2TTRSLC6A2
SCHEMBL7861699 0.74 KDM4E (0.36) SLC6A2HSP90AA1MAPTHPGD
SCHEMBL7870174 0.73 GAA (0.50) MAPTHPGDEPAS1
SCHEMBL11755731 0.72 SLC6A3 (0.49) SLC6A3SLC6A4KCNH2TTRSLC6A2
SCHEMBL3619566 0.72 TRPV4 (0.31)
SCHEMBL7873576 0.71 MAPT (0.46) SLC6A3SLC6A4SLC6A2LMNAMAPT
SCHEMBL9140608 0.71 TRPV4 (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed