Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869070 | 0.77 | BCHE (0.50) | FNTAFNTBLTB4R2LPAR1BRS3 | |
| SCHEMBL7867499 | 0.70 | BMP1 (0.47) | FNTAFNTBLTB4R2 | |
| SCHEMBL7869068 | 0.69 | ADRB1 (0.38) | LTB4R2BRS3 | |
| SCHEMBL10192976 | 0.68 | FNTA (0.51) | FNTAFNTBLTB4R2BRS3 | |
| SCHEMBL7871098 | 0.68 | FNTA (0.49) | FNTAFNTBLTB4R2 | |
| SCHEMBL10193047 | 0.68 | FNTA (0.54) | FNTAFNTBBRS3 | |
| SCHEMBL6628777 | 0.67 | FNTA (0.62) | FNTAFNTB | |
| SCHEMBL7870287 | 0.66 | AGTR1 (0.44) | FNTAFNTBLTB4R2 | |
| SCHEMBL629682 | 0.66 | FNTA (0.69) | FNTAFNTBLTB4R2 | |
| SCHEMBL6626875 | 0.66 | FNTA (0.77) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |