Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239387 | 0.67 | ALDH1A1 (0.46) | ALDH1A1CA2CTSSCTSKTSHR | |
| SCHEMBL75648 | 0.66 | ALDH1A1 (0.44) | ALDH1A1CA2CTSSCTSKTSHR | |
| SCHEMBL25354485 | 0.64 | ALDH1A1 (0.39) | ALDH1A1SLC6A4CA2CTSSCTSK | |
| SCHEMBL6858801 | 0.64 | ALDH1A1 (0.42) | ALDH1A1CA2CTSSCTSKTSHR | |
| SCHEMBL16096610 | 0.64 | ALDH1A1 (0.46) | ALDH1A1CA2CTSSCTSKTSHR | |
| SCHEMBL14741312 | 0.62 | SLC6A2 (0.51) | ALDH1A1CTSDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8766756 | 0.62 | MAOA (0.48) | SLC6A2SLC6A4SLC6A3MC4RGBA1 | |
| SCHEMBL7867639 | 0.62 | SLC6A2 (0.51) | ALDH1A1CTSDSLC6A2SLC6A4SLC6A3 | |
| Diphenylmethane SCHEMBL29262556 | 0.62 | CALM1 (0.46) | ALDH1A1CTSDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL121312 | 0.62 | SLC6A2 (0.51) | ALDH1A1CTSDSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310216-B1 | Special 3-azabicyclo[3.1.0]hexanes, method for producing and modifying the same, and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | disclosed |
| EP-1000026-A1 | SPECIAL 3-AZABICYCLO 3.1.0]HEXANES, METHOD FOR PRODUCING AND MODIFYING THE SAME, AND THEIR USE | Bayer Aktiengesellschaft (DE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006368-A1 | SPECIAL 3-AZABICYCLO[3.1.0]HEXANES, METHOD FOR PRODUCING AND MODIFYING THE SAME, AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-11 | — | — | WO | disclosed |