Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | KDM1A | O60341 | 7/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802127 | 0.71 | MAOA (0.50) | MAOAMAOBKDM1ARCOR1 | |
| SCHEMBL8765779 | 0.70 | MC4R (0.37) | MAOAMAOBKDM1AGBA1MC4R | |
| SCHEMBL16608218 | 0.70 | LMNA (0.42) | MAOAMAOBKDM1AGBA1MC4R | |
| SCHEMBL16608271 | 0.70 | MAOA (0.36) | MAOAMAOBKDM1AGBA1MC4R | |
| SCHEMBL18373227 | 0.70 | MAOA (0.36) | MAOAMAOBKDM1AGBA1MC4R | |
| SCHEMBL9407229 | 0.69 | MEN1 (0.34) | MAOAMAOBKDM1AGBA1MC4R | |
| SCHEMBL15922992 | 0.69 | HSD11B1 (0.54) | MAOAMAOBKDM1ARCOR1 | |
| SCHEMBL15922990 | 0.69 | HSD11B1 (0.54) | MAOAMAOBKDM1ARCOR1 | |
| SCHEMBL7867641 | 0.68 | MC4R (0.49) | GBA1MC4R | |
| SCHEMBL23805616 | 0.67 | GRIN2B (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629189-B1 | PREPARATION OF INTERMEDIATES IN THE SYNTHESIS OF QUINOLINE ANTIBIOTICS | PFIZER (US) | 1997-08-06 | — | — | EP | disclosed |
| US-5298629-A | Intermediates in the synthesis of quinoline antibiotics | PFIZER INC. (US) | 1994-03-29 | — | — | US | disclosed |
| US-5256791-A | Preparation of intermediates in the synthesis of quinoline antibiotics | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |