Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574869 | 0.93 | CA1 (0.47) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7871678 | 0.93 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7869478 | 0.93 | KDM4E (0.44) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7869429 | 0.91 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL9574752 | 0.91 | L3MBTL1 (0.53) | ALDH1A1MEN1KMT2ALMNAP4HTM | |
| SCHEMBL7870523 | 0.91 | MEN1 (0.47) | ALDH1A1MEN1KMT2ALMNARAB9A | |
| SCHEMBL7870440 | 0.90 | PTPN1 (0.49) | ALDH1A1LMNAKDM4EPOLBGAA | |
| SCHEMBL7870511 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7874550 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7870468 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |