Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574662 | 0.94 | CA1 (0.40) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9574748 | 0.94 | RAB9A (0.41) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7870461 | 0.93 | ALDH1A1 (0.49) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7870343 | 0.92 | RAB9A (0.42) | KDM4ELMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL7862676 | 0.92 | RAB9A (0.46) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7862669 | 0.91 | CYP1A2 (0.45) | LMNAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9018068 | 0.90 | P4HTM (0.43) | KDM4ELMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL7871648 | 0.90 | RAB9A (0.39) | LMNAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL8870568 | 0.89 | P4HTM (0.47) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7862841 | 0.88 | CA1 (0.40) | LMNAALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |