Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867696 | 0.92 | LMNA (0.42) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7869429 | 0.91 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL9018176 | 0.91 | LMNA (0.47) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7870461 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL8868665 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7862691 | 0.88 | MEN1 (0.41) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7870515 | 0.87 | POLB (0.44) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL9018549 | 0.86 | LMNA (0.43) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL9574869 | 0.86 | CA1 (0.47) | ALDH1A1MEN1KMT2ARAB9AP4HTM | |
| SCHEMBL7870511 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |