Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528462 | 0.99 | ABCB1 (0.41) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL13079882 | 0.89 | ABCB1 (0.38) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4023253 | 0.78 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9371324 | 0.78 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9363607 | 0.78 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL481900 | 0.78 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL482249 | 0.78 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL6273195 | 0.78 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9767316 | 0.77 | ABCB1 (0.46) | ABCB1ABCC9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9529091 | 0.76 | ABCC9 (0.42) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571822-B1 | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5418232-A | Hypotensive, increases renal blood flow | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0571822-A1 | Diazabicycloalkene derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |