Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870503 | 0.99 | ABCB1 (0.42) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL13079882 | 0.87 | ABCB1 (0.38) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9529091 | 0.77 | ABCC9 (0.42) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL482249 | 0.77 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL481900 | 0.77 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL6273195 | 0.77 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9371324 | 0.77 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL4023253 | 0.77 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9363607 | 0.77 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL12162436 | 0.76 | OPRD1 (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536424-A1 | NOVEL BENZOPYRAN DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |