Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768154 | 0.91 | TRPV4 (0.33) | HDAC3HDAC1HDAC2HDAC8SLC2A1 | |
| SCHEMBL787150 | 0.86 | ACHE (0.33) | HDAC3HDAC1HDAC2HDAC8SLC2A1 | |
| SCHEMBL380826 | 0.85 | CHRM2 (0.47) | SLC2A1CHRM2 | |
| SCHEMBL768103 | 0.83 | HRH3 (0.41) | HRH3SLC2A1CHRM2CARM1PRMT6 | |
| SCHEMBL768708 | 0.81 | CHRM2 (0.39) | HRH3SLC2A1CHRM2CARM1PRMT6 | |
| SCHEMBL768889 | 0.79 | CHRM2 (0.39) | HRH3SLC2A1CHRM2CARM1PRMT6 | |
| SCHEMBL769264 | 0.79 | CHRM2 (0.39) | HRH3SLC2A1CHRM2CARM1PRMT6 | |
| SCHEMBL768533 | 0.79 | HRH3 (0.41) | HRH3SLC2A1CHRM2 | |
| SCHEMBL767767 | 0.79 | HRH3 (0.41) | HRH3SLC2A1CHRM2 | |
| SCHEMBL768998 | 0.79 | HTR2A (0.35) | HRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | HDAC3 202/4885HDAC1 414/4885HDAC2 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.