Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.55 |
| ▸ | RARB | P10826 | 5/20 | 0.55 |
| ▸ | RARG | P13631 | 5/20 | 0.55 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | BLVRB | P30043 | 1/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872206 | 1.00 | RARA (0.55) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7878314 | 0.89 | PKM (0.62) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7878312 | 0.89 | PKM (0.62) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7872280 | 0.86 | CYP26A1 (0.51) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7872275 | 0.86 | CYP26A1 (0.51) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7899451 | 0.84 | CYP26A1 (0.60) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7899449 | 0.84 | CYP26A1 (0.60) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7872241 | 0.80 | RARB (0.50) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL7872239 | 0.80 | RARB (0.50) | RARARARBRARGCYP26A1KMT2A | |
| SCHEMBL18664648 | 0.79 | PKM (0.60) | KMT2AMEN1ALDH1A1SNCAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |