Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 5/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.47 |
| ▸ | ITK | Q08881 | 5/20 | 0.46 |
| ▸ | BTK | Q06187 | 4/20 | 0.46 |
| ▸ | AXL | P30530 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570632 | 0.89 | AAK1 (0.52) | AAK1NTRK1ITKBTKAXL | |
| SCHEMBL7879449 | 0.86 | RIPK1 (0.47) | AAK1KITNTRK1ITKBTK | |
| SCHEMBL298800 | 0.86 | TNIK (0.54) | AAK1KITNTRK1ITKBTK | |
| SCHEMBL858632 | 0.85 | NTRK1 (0.64) | AAK1KITNTRK1ITKAXL | |
| SCHEMBL856998 | 0.82 | KIT (0.57) | AAK1KITNTRK1ITKAXL | |
| SCHEMBL299272 | 0.82 | CAMKK2 (0.61) | AAK1KITNTRK1ITKAXL | |
| SCHEMBL3699186 | 0.81 | NTRK1 (0.64) | AAK1KITNTRK1ITKAXL | |
| SCHEMBL858562 | 0.80 | KIT (0.66) | AAK1KITNTRK1AXLDYRK1A | |
| SCHEMBL416155 | 0.80 | AAK1 (0.53) | AAK1KITNTRK1ITKAXL | |
| SCHEMBL27101328 | 0.80 | AAK1 (0.53) | AAK1KITNTRK1ITKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129570-A1 | SOLID FORMS OF SULFONAMIDES AND AMINO ACIDS | PLEXXIKON, INC. (US) | 2010-11-11 | — | — | WO | disclosed |