Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874613 | 0.94 | CES2 (0.40) | CES2CES1CSNK1EDNM1HIF1A | |
| Iodide SCHEMBL5086690 | 0.94 | CSNK1E (0.41) | CES2CES1CSNK1EDNM1HIF1A | |
| Bromide SCHEMBL5091727 | 0.94 | DNM1 (0.43) | CES2CES1CSNK1EDNM1HIF1A | |
| Iodide SCHEMBL11105595 | 0.94 | CSNK1E (0.41) | CES2CES1CSNK1EDNM1HIF1A | |
| Bromide SCHEMBL5859727 | 0.94 | DNM1 (0.43) | CES2CES1CSNK1EDNM1HIF1A | |
| Hydrochloric Acid SCHEMBL5088545 | 0.94 | MEN1 (0.42) | CES2CES1CSNK1EDNM1HIF1A | |
| Water SCHEMBL4392333 | 0.94 | CSNK1E (0.41) | CES2CES1CSNK1EDNM1HIF1A | |
| Bromide SCHEMBL5087698 | 0.92 | BDKRB2 (0.41) | CES2CES1CSNK1EDNM1HIF1A | |
| Iodide SCHEMBL5091883 | 0.92 | HIF1A (0.41) | CES2CES1CSNK1EDNM1HIF1A | |
| Hydrochloric Acid SCHEMBL5085116 | 0.92 | BDKRB2 (0.41) | CES2CES1CSNK1EDNM1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316575-B1 | MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | claimed |