Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429163 | 0.83 | METAP2 (0.41) | SLC6A3SLC18A3F2RL1NPY5RCTSS | |
| SCHEMBL7393950 | 0.79 | SLC18A3 (0.34) | SLC6A3SLC18A3F2RL1MEN1KMT2A | |
| SCHEMBL4287736 | 0.78 | EPHX2 (0.40) | SLC6A3MEN1KMT2A | |
| SCHEMBL7876940 | 0.78 | PSMB5 (0.33) | CTSSIDO1 | |
| SCHEMBL7486546 | 0.76 | MGLL (0.40) | MEN1KMT2A | |
| SCHEMBL7383746 | 0.76 | MEN1 (0.35) | SLC6A3MEN1KMT2A | |
| SCHEMBL7359462 | 0.73 | IDO1 (0.42) | SLC18A3IDO1PRCPKCNH2HRH3 | |
| SCHEMBL7953190 | 0.73 | NPC1 (0.37) | MEN1KMT2A | |
| SCHEMBL7381198 | 0.72 | CTSL (0.34) | SLC6A3MEN1KMT2ACTSS | |
| SCHEMBL7421314 | 0.72 | CTSL (0.34) | SLC6A3MEN1KMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329400-B1 | INHIBITION OR ANTAGONISM OF MATRIX METALLOPROTEASES, AND/OR TUMOR NECROSIS FACTOR-ALPHA; EXTRACELLULAR MATRIX DEGRADATION, INHIBITION OF SHEDDING OF CELL SURFACE PROTEIN ECTODOMAINS AND CD23 PROTEOLYSIS | GLAXO WELLCOME INC. | 2001-12-11 | — | — | US | disclosed |