Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879600 | 0.78 | HSP90AA1 (0.47) | ALDH1A1 | |
| SCHEMBL7877387 | 0.77 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2SGMS1LMNA | |
| SCHEMBL7873778 | 0.76 | CYP19A1 (0.54) | ALDH1A1POLBSMN1; SMN2LMNAHTT | |
| SCHEMBL9020952 | 0.76 | ALDH1A1 (0.53) | ALDH1A1POLBSMN1; SMN2SGMS1AKR1C3 | |
| SCHEMBL7109149 | 0.73 | ALDH1A1 (1.00) | ALDH1A1POLBSMN1; SMN2SGMS1AKR1C3 | |
| SCHEMBL9372954 | 0.72 | SIGMAR1 (0.53) | ALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL7868628 | 0.71 | ALDH1A1 (0.77) | ALDH1A1POLBSMN1; SMN2SGMS1LMNA | |
| SCHEMBL7879555 | 0.71 | TDP1 (0.47) | ALDH1A1POLBSMN1; SMN2LMNAHTT | |
| SCHEMBL29260159 | 0.71 | ALDH1A1 (0.81) | ALDH1A1POLBSMN1; SMN2SGMS1LMNA | |
| SCHEMBL7873784 | 0.70 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |