Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803053 | 0.93 | THRB (0.33) | THRBTHRA | |
| SCHEMBL7804595 | 0.89 | THRB (0.34) | THRBTHRATSHR | |
| SCHEMBL7174976 | 0.80 | THRB (0.38) | THRBTHRAHPGDTSHR | |
| SCHEMBL21693856 | 0.79 | THRB (0.37) | THRBTHRAHPGDTSHR | |
| SCHEMBL25385326 | 0.78 | CASP1 (0.43) | THRBTHRAALDH1A1 | |
| SCHEMBL15173410 | 0.78 | THRB (0.36) | THRBTHRAHPGDTSHR | |
| SCHEMBL8038236 | 0.76 | AOC3 (0.40) | HPGD | |
| SCHEMBL3171202 | 0.74 | THRB (0.40) | THRBTHRA | |
| SCHEMBL238275 | 0.72 | THRB (0.41) | THRBTHRAHPGDTSHRALDH1A1 | |
| SCHEMBL27740012 | 0.71 | THRB (0.40) | THRBTHRAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6309708-B1 | ORGANOMETALLIC POLYMERS | DAIKIN INDUSTRIES, LTD. (JP) | 2001-10-30 | — | — | US | disclosed |