Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028264 | 0.92 | KDM4E (0.42) | AOC3KMT2AKDM4EL3MBTL1CDC25A | |
| SCHEMBL2326069 | 0.84 | AOC3 (0.39) | AOC3KMT2AKDM4ECYP2C9HPGD | |
| SCHEMBL2326062 | 0.84 | AOC3 (0.39) | AOC3KMT2AKDM4ECYP2C9HPGD | |
| SCHEMBL7174976 | 0.83 | THRB (0.38) | HPGD | |
| SCHEMBL21693856 | 0.82 | THRB (0.37) | HPGD | |
| SCHEMBL11566786 | 0.82 | AOC3 (0.46) | AOC3KMT2AKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL25385326 | 0.81 | CASP1 (0.43) | AOC3KDM4EHTT | |
| SCHEMBL15173410 | 0.81 | THRB (0.36) | HPGD | |
| SCHEMBL5450041 | 0.81 | AOC3 (0.36) | AOC3KDM4ECYP2C9HPGDCYP2C19 | |
| SCHEMBL3173706 | 0.79 | LMNA (0.40) | KMT2ACYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |