Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9819144 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL10339061 | 0.82 | CA4 (0.50) | — | |
| SCHEMBL3404050 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL29859 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL1634173 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL7100054 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL438334 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL1532630 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL11572159 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL2183651 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6309441-B1 | ADDING TO MOLTEN SLAG HALIDE FLUX CONTAINING REDUCING AGENT, RARE EARTH OXIDE, TRANSITION METAL COMPOUND AND BORON COMPOUND; PLACING NON-CONSUMABLE ELECTRODE IN CONTACT WITH ELECTROSLAG; PASSING CURRENT TO REDUCE AND FROM ALLOY | GENERAL ELECTRIC COMPANY | 2001-10-30 | — | — | US | disclosed |
| WO-1998015667-A1 | REDUCTION-MELTING PROCESS TO FORM RARE EARTH-TRANSITION METAL ALLOYS AND THE ALLOYS | GENERAL ELECTRIC COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |