Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866953 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1TSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7862199 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL7873618 | 0.80 | MEN1 (0.64) | SMN1; SMN2KDM4EALDH1A1TDP1EPHX2 | |
| Hydrochloric Acid SCHEMBL7866916 | 0.79 | MEN1 (0.63) | SMN1; SMN2KDM4EALDH1A1TDP1EPHX2 | |
| SCHEMBL7869922 | 0.77 | MAPT (0.56) | SMN1; SMN2KDM4EALDH1A1EPHX2MEN1 | |
| SCHEMBL7868849 | 0.77 | KDR (0.52) | SMN1; SMN2KDM4EALDH1A1HRH3MEN1 | |
| Hydrochloric Acid SCHEMBL7868840 | 0.76 | MAPT (0.55) | SMN1; SMN2KDM4EALDH1A1EPHX2MEN1 | |
| SCHEMBL7866966 | 0.75 | BCAT2 (0.57) | SMN1; SMN2KDM4EALDH1A1TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL7867070 | 0.75 | MAPT (0.44) | SMN1; SMN2KDM4EALDH1A1TDP1EPHX2 | |
| SCHEMBL7866940 | 0.75 | HTT (0.58) | SMN1; SMN2KDM4EALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |