Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867548 | 0.89 | NPSR1 (0.51) | NPSR1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7874397 | 0.88 | ALDH1A1 (0.56) | NPSR1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7872611 | 0.80 | NPSR1 (0.73) | NPSR1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7876133 | 0.78 | NPSR1 (0.71) | NPSR1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL7867590 | 0.78 | NPSR1 (0.71) | NPSR1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL14730658 | 0.77 | LMNA (0.65) | NPSR1SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL3666480 | 0.73 | AKR1C3 (0.63) | NPSR1SMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL8863111 | 0.73 | NPSR1 (0.55) | NPSR1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL13753812 | 0.72 | TAS1R3 (0.61) | NPSR1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7174425 | 0.72 | PDE4A (0.53) | NPSR1SMN1; SMN2MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800505-B1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORP (US) | 2001-09-26 | — | — | EP | claimed |