Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870556 | 0.95 | PPARA (0.46) | MAPTLMNAPOLBMEN1KMT2A | |
| SCHEMBL7870557 | 0.93 | POLB (0.40) | MAPTLMNAPOLBMEN1KMT2A | |
| SCHEMBL7870468 | 0.92 | ALDH1A1 (0.43) | LMNAPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7867891 | 0.90 | ALDH1A1 (0.43) | LMNAPOLBMEN1KMT2ANPC1 | |
| SCHEMBL8868704 | 0.90 | P4HTM (0.48) | MAPTLMNAPOLBMEN1KMT2A | |
| SCHEMBL7869440 | 0.89 | MEN1 (0.45) | MAPTLMNAMEN1KMT2APPARA | |
| SCHEMBL7870523 | 0.88 | MEN1 (0.47) | MAPTLMNAMEN1KMT2APPARA | |
| SCHEMBL7871652 | 0.87 | NLRP3 (0.54) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9574900 | 0.87 | LMNA (0.45) | MAPTLMNAMEN1KMT2APPARA | |
| SCHEMBL8868529 | 0.85 | PPARA (0.49) | MAPTLMNAPOLBPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |