Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235764 | 0.88 | PIN1 (0.47) | PIN1ALDH1A1MAPT | |
| SCHEMBL11131384 | 0.82 | PIN1 (0.53) | PIN1ALDH1A1EPHX2KCNQ2 | |
| SCHEMBL11666042 | 0.81 | PIN1 (0.51) | PIN1EPHX2KCNQ2 | |
| SCHEMBL21144646 | 0.80 | PIN1 (0.54) | PIN1ALDH1A1KCNQ2 | |
| SCHEMBL11305795 | 0.80 | PIN1 (0.54) | PIN1ALDH1A1KCNQ2 | |
| SCHEMBL9540395 | 0.80 | PIN1 (0.54) | PIN1ALDH1A1KCNQ2 | |
| SCHEMBL30191225 | 0.80 | PIN1 (0.54) | PIN1ALDH1A1KCNQ2 | |
| SCHEMBL12431131 | 0.79 | PIN1 (0.60) | PIN1KCNQ2 | |
| SCHEMBL907688 | 0.79 | PIN1 (0.60) | PIN1KCNQ2 | |
| SCHEMBL2790690 | 0.79 | PIN1 (0.60) | PIN1KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6315928-B1 | FOR OPHTHALMIC LENSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-11-13 | — | — | US | disclosed |