Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874907 | 0.88 | PIN1 (0.51) | PIN1ALDH1A1MAPT | |
| SCHEMBL21144646 | 0.75 | PIN1 (0.54) | PIN1ALDH1A1 | |
| SCHEMBL9540395 | 0.75 | PIN1 (0.54) | PIN1ALDH1A1 | |
| SCHEMBL11305795 | 0.75 | PIN1 (0.54) | PIN1ALDH1A1 | |
| SCHEMBL30191225 | 0.75 | PIN1 (0.54) | PIN1ALDH1A1 | |
| SCHEMBL11233523 | 0.74 | CYP19A1 (0.53) | CYP19A1FNTAFNTBSIGMAR1ALDH1A1 | |
| SCHEMBL11131384 | 0.74 | PIN1 (0.53) | PIN1ALDH1A1 | |
| Pyridine SCHEMBL19209999 | 0.74 | PIN1 (0.49) | PIN1CYP19A1CYP17A1CYP11B2ALDH1A1 | |
| SCHEMBL11666042 | 0.73 | PIN1 (0.51) | PIN1GAA | |
| SCHEMBL4830828 | 0.72 | PIN1 (0.62) | PIN1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |