Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30191225 | 0.83 | PIN1 (0.54) | PIN1KCNQ2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL11305795 | 0.83 | PIN1 (0.54) | PIN1KCNQ2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL21144646 | 0.83 | PIN1 (0.54) | PIN1KCNQ2MTNR1AMTNR1BCRBN | |
| SCHEMBL11131384 | 0.81 | PIN1 (0.53) | PIN1KCNQ2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9541731 | 0.80 | PIN1 (0.58) | PIN1KCNQ2CRBNIDO1PDPK1 | |
| SCHEMBL7874907 | 0.80 | PIN1 (0.51) | PIN1KCNQ2ALDH1A1 | |
| SCHEMBL11666042 | 0.80 | PIN1 (0.51) | PIN1KCNQ2MTNR1AMTNR1B | |
| SCHEMBL4830828 | 0.80 | PIN1 (0.62) | PIN1KCNQ2CRBNIDO1PDPK1 | |
| SCHEMBL8974693 | 0.79 | PIN1 (0.50) | PIN1KCNQ2MTNR1AMTNR1BCRBN | |
| SCHEMBL2790690 | 0.78 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003033-A1 | CARBONATE-SUBSTITUTED IMIDAZO[4,5-d] PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G. D. SEARLE & CO. (US) | 1993-02-18 | — | — | WO | claimed |
| WO-1993003033-A1 | CARBONATE-SUBSTITUTED IMIDAZO[4,5-d] PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G. D. SEARLE & CO. (US) | 1993-02-18 | — | — | WO | disclosed |
| WO-1993003033-A1 | CARBONATE-SUBSTITUTED IMIDAZO[4,5-d] PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G. D. SEARLE & CO. (US) | 1993-02-18 | — | — | WO | disclosed |