Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | IDO1 | P14902 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587743 | 0.88 | GAA (0.48) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL7872427 | 0.86 | IDO1 (0.46) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL8607204 | 0.86 | IDO1 (0.50) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL8607422 | 0.85 | IDO1 (0.45) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL7863563 | 0.83 | IDO1 (0.46) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL8607489 | 0.83 | IDO1 (0.46) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL11248747 | 0.82 | KDM4E (0.60) | GAAKDM4ECYP1A2GLAMAPK1 | |
| SCHEMBL8607817 | 0.81 | IDO1 (0.43) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL7875517 | 0.80 | GAA (0.43) | GAAIDO1KDM4ECYP1A2TGFBR1 | |
| SCHEMBL12549923 | 0.80 | IDO1 (0.44) | GAAIDO1KDM4ECYP1A2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9249666-A | — | — | None | — | — | JP | disclosed |
| US-20010051631-A1 | Tricyclic compounds, their production and use | TAKATANI MUNEO (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6251905-B1 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| US-5958942-A | HAVING EXCELLENT PDGF-INHIBITING ACTIVITIES, ANTIHYPERTENSIVE ACTIVITIES, ACTIVITIES OF AMELIORATING RENAL DISEASES AND ACTIVITIES OF LOWERING LIPID LEVEL. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| WO-1998029136-A1 | STABILIZED TRICYCLIC COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-09 | — | — | WO | disclosed |
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
| JP-H09249666-A | PRODUCTION OF TRICYCLIC COMPOUND AND ITS INTERMEDIATE | TAKEDA CHEM IND LTD | 1997-09-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051631-A1 | Tricyclic compounds, their production and use | PDGFA, HGF, REN | GAA 3830/4885IDO1 795/4885KDM4E 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.