SCHEMBL7876076

SCHEMBL7876076

Nc1ccc(Oc2ccccc2Sc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.53
NCOA3 Q9Y6Q9 1/20 0.53
MAOA P21397 2/20 0.52
ALDH1A1 P00352 4/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
NLRP3 Q96P20 1/20 0.43
HPGD P15428 2/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 4/20 0.41
KDM4E B2RXH2 2/20 0.41
MITF O75030 1/20 0.40
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11019469 0.93 MAOA (0.52) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL3145573 0.89 NCOA1 (0.55) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL14654309 0.87 TSHR (0.44) ALDH1A1TSHRTDP1KMT2AHPGD
SCHEMBL9780318 0.82 MAOB (0.56) MAOAALDH1A1CYP3A4MEN1KMT2A
SCHEMBL7225717 0.82 NCOA1 (0.55) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL9557282 0.81 MAPT (0.47) ALDH1A1TDP1MEN1KMT2AHPGD
SCHEMBL9557543 0.79 KDM4E (0.41) TSHRKMT2AMAPTKDM4EGAA
SCHEMBL11239908 0.79 NCOA1 (0.51) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL28007611 0.79 NCOA1 (0.51) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL30580501 0.78 LTA4H (0.55) ALDH1A1MEN1KMT2AHPGDCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6319597-B1 MULTILAYER POLYIMIDE FILM FROM TETRACARBOXYLIC ACID AND BIS/AMINOPHENYL ETHER PENTAERYTHRITOL UBE INDUSTRIES, LTD. (JP) 2001-11-20 US disclosed
EP-0145727-A4 IMPROVED POLYAMIDE-ACIDS AND POLYIMIDES. M & T CHEMICALS INC (US) 1985-09-18 EP disclosed
EP-0145727-A1 IMPROVED POLYAMIDE-ACIDS AND POLYIMIDES M & T CHEMICALS, INC. (US) 1985-06-26 EP disclosed
WO-1984004313-A1 IMPROVED POLYAMIDE-ACIDS AND POLYIMIDES M & T CHEMICALS INC (US) 1984-11-08 WO disclosed