Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654309 | 0.89 | TSHR (0.44) | MAPTKDM4EMAPK1NSD2SLC6A9 | |
| SCHEMBL16682061 | 0.88 | L3MBTL1 (0.45) | MAPTKDM4EMAPK1NSD2SLC6A9 | |
| SCHEMBL3289071 | 0.82 | AR (0.56) | MAPTKDM4EMAPK1NSD2SLC6A9 | |
| SCHEMBL7876076 | 0.81 | NCOA1 (0.53) | MAPTKDM4EMAPK1NSD2SIRT1 | |
| SCHEMBL9557543 | 0.81 | KDM4E (0.41) | MAPTKDM4EMAPK1NSD2SLC6A9 | |
| SCHEMBL795029 | 0.79 | SIRT1 (0.54) | MAPTKDM4EMAPK1NSD2SIRT1 | |
| SCHEMBL11060851 | 0.79 | SIRT1 (0.47) | MAPTKDM4EMAPK1NSD2SLC6A9 | |
| Water SCHEMBL11132055 | 0.79 | KDM4E (0.42) | MAPTKDM4EMAPK1NSD2SLC6A9 | |
| SCHEMBL30580493 | 0.78 | SLC6A9 (0.46) | MAPK1SLC6A9TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9780318 | 0.77 | MAOB (0.56) | MAPTKDM4EMAPK1NSD2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5271858-A | Field dependent fluids containing electrically conductive tin oxide coated materials | ENSCI INC. (US) | 1993-12-21 | — | — | US | disclosed |
| US-3939084-A | Functional fluid compositions containing substituted pyrimidines | MONSANTO COMPANY (US) | 1976-02-17 | — | — | US | disclosed |