SCHEMBL1908071

SCHEMBL1908071

C=CCc1cc(O)ccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
TSHR P16473 1/20 0.52
ALOX5 P09917 1/20 0.47
PTGS2 P35354 1/20 0.47
EGFR P00533 3/20 0.45
LCK P06239 3/20 0.45
TDP1 Q9NUW8 3/20 0.43
MAPT P10636 3/20 0.43
GABRA1 P14867 2/20 0.43
GABRB2 P47870 2/20 0.43
RGS12 O14924 1/20 0.43
CAMKK2 Q96RR4 1/20 0.43
NOX4 Q9NPH5 1/20 0.43
ESR1 P03372 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7806960 0.89 GABRA1 (0.43) ALDH1A1CA12CA1CA2CA7
SCHEMBL3089041 0.86 HSD17B1 (0.50) ALDH1A1CA12CA1CA2CA7
SCHEMBL15824990 0.86 GABRA1 (0.41) ALDH1A1CA12CA1CA2CA7
SCHEMBL3283491 0.84 HSP90AB1 (0.42) ALDH1A1MAPTGABRA1GABRB2ESR1
SCHEMBL1920791 0.84 POLB (0.41) ALDH1A1CA12CA1CA2CA7
SCHEMBL28933964 0.84 MEN1 (0.57) ALDH1A1MAPTESR1ESR2MEN1
SCHEMBL278481 0.83 KDM4E (0.46) ALDH1A1CA12CA1CA2CA7
SCHEMBL2053985 0.82 GABRA1 (0.41) ALDH1A1TSHRMAPTGABRA1GABRB2
SCHEMBL29230369 0.82 CA12 (0.56) ALDH1A1CA12CA1CA2CA7
SCHEMBL2852455 0.81 ALDH1A1 (0.53) ALDH1A1TSHRPTGS2TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2450027-B1 DENTAL COMPOSITIONS HAVING SPECIAL FUNCTIONALITY AND TRI-BARREL PACKAGING KERR CORP (US) 2023-01-11 EP claimed
WO-2020120837-A1 ANTIMICROBIAL POLYMER COMPOSITION PREMIX OY (FI) 2020-06-18 WO claimed
EP-3666075-A1 ANTIMICROBIAL POLYMER COMPOSITION Premix Oy (FI) 2020-06-17 EP claimed
EP-3374357-B1 DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS ENI SPA (IT) 2019-10-02 EP claimed
US-10098908-B2 Method of treating a mammalian teat and related compositions Zurex PharmAgra, Inc. (US) 2018-10-16 US claimed
US-20180264080-A1 TOPICAL APPLICATIONS OF Kv1.3 CHANNEL BLOCKING PEPTIDES TO TREAT SKIN INFLAMMATION KINETA ONE, LLC (US) 2018-09-20 US claimed
WO-2016112208-A2 TOPICAL APPLICATIONS OF KV1.3 CHANNEL BLOCKING PEPTIDES TO TREAT SKIN INFLAMMATION KINETA ONE, LLP (US) 2016-07-14 WO claimed
US-20150250816-A1 METHOD OF TREATING A MAMMALIAN TEAT AND RELATED COMPOSITIONS ZUREX PHARMAGRA INC (US) 2015-09-10 US claimed
US-20120301407-A1 METHOD OF TREATING A MAMMALIAN TEAT AND RELATED COMPOSITIONS Zurex PharmAgra, Inc. (US) 2012-11-29 US claimed
US-8303821-B2 Reduction of antimicrobial compound levels during product dispensing ROHM AND HAAS COMPANY (US) 2012-11-06 US claimed
WO-2006110961-A2 NOVEL CORROSION INHIBITING MATERIALS A J SCIENTIFIC PTY LTD (AU) 2006-10-26 WO claimed
EP-1368016-B1 PARENTERAL DOSAGE FORMS COMPRISING A SUSPENSION OF TRAMADOL SALT AND DICLOFENAC SALT GRUENENTHAL GMBH (DE) 2006-04-19 EP claimed
US-6875447-B2 Parenteral dosage forms comprising a suspension of tramadol salt and diclofenac salt GRUNENTHAL GMBH (DE) 2005-04-05 US claimed
US-6830782-B2 (1) the step of activation-treatment and (2) the step of a hydrophilic polymer-treatment in this order, optionally followed by monomer grafted KB INTERNATIONAL, LLC 2004-12-14 US claimed
US-20030203037-A1 Dosage forms which can be administered parenterally and comprise a suspension of the salt of tramadol and diclofenac GRUNENTHAL GMBH (DE) 2003-10-30 US claimed
US-20030087982-A1 (1) the step of activation-treatment and (2) the step of a hydrophilic polymer-treatment in this order, optionally followed by monomer grafted KB INTERNATIONAL, LLC 2003-05-08 US claimed
EP-1164157-A1 METHOD OF MODIFYING POLYMERIC MATERIAL AND USE THEREOF Kanazawa, Hitoshi (JP) 2001-12-19 EP claimed
EP-0974342-B1 Single phase transparent aqueous composition OREAL (FR) 2001-09-12 EP claimed
CN-1309567-A FSH and FSH variant formulations, products and methods LILLY CO ELI (US) 2001-08-22 CN claimed
EP-0126364-B1 METABOLICALLY ACTIVE PREPARATIONS OBTAINED FROM YEAST OF ANY TYPE HASUNOR A.G. (CH) 1987-09-09 EP claimed