Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761354 | 0.81 | HSD17B10 (0.49) | MEN1KMT2AALDH1A1ADRA1A | |
| SCHEMBL6761350 | 0.81 | HSD17B10 (0.49) | MEN1KMT2AALDH1A1ADRA1A | |
| SCHEMBL825343 | 0.78 | SMN1; SMN2 (0.49) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8759049 | 0.78 | L3MBTL1 (0.48) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27827515 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8863111 | 0.73 | NPSR1 (0.55) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4392054 | 0.73 | ADRA1A (0.40) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL7040353 | 0.72 | CYP1A2 (0.49) | ALDH1A1MAPTCYP1A2TSHRCYP2C19 | |
| SCHEMBL537188 | 0.72 | FFAR1 (0.44) | LMNAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL6704501 | 0.72 | MEN1 (0.41) | MEN1KMT2AALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800505-B1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORP (US) | 2001-09-26 | — | — | EP | claimed |
| EP-0548217-B1 | PROCESS FOR THE PREPARATION OF C-TERMINALLY AMIDATED PEPTIDES | BUCHARDT OLE (DK) | 1997-04-09 | — | — | EP | disclosed |
| US-5580751-A | REACTING A PEPTIDE WITH A NUCLEOPHILIC AMINE IN THE PRESENCE OF TRYPSIN OR A CARBOXYPEPIDASE; NONENZYMATICALLY CLEAVING TO FORM THE PRODUCT | CARLSBERG A/S (DK) | 1996-12-03 | — | — | US | disclosed |
| EP-0548217-A1 | PROCESS FOR THE PREPARATION OF C-TERMINALLY AMIDATED PEPTIDES. | BUCHARDT OLE (DK) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005271-A1 | PROCESS FOR THE PREPARATION OF C-TERMINALLY AMIDATED PEPTIDES | BUCHARDT OLE (DK) | 1992-04-02 | — | — | WO | disclosed |