Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878136 | 1.00 | CTSS (0.43) | CTSSCTSKCA12CA9ALDH1A1 | |
| SCHEMBL9972470 | 0.87 | CTSS (0.44) | CTSSCTSKALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3265338 | 0.87 | CTSS (0.44) | CTSSCTSKALDH1A1TSHRL3MBTL1 | |
| SCHEMBL5990092 | 0.87 | CTSS (0.44) | CTSSCTSKALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7880337 | 0.85 | METAP2 (0.46) | CTSSCTSKCA12CA9ALDH1A1 | |
| SCHEMBL8430244 | 0.85 | METAP2 (0.46) | CTSSCTSKCA12CA9ALDH1A1 | |
| SCHEMBL7871939 | 0.85 | METAP2 (0.46) | CTSSCTSKCA12CA9ALDH1A1 | |
| SCHEMBL1983218 | 0.84 | MAPK1 (0.54) | CTSSCTSKALDH1A1MAPK1LMNA | |
| SCHEMBL28501721 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRL3MBTL1CYP2C9GAA | |
| SCHEMBL1983219 | 0.84 | MAPK1 (0.54) | CTSSCTSKALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333176-B1 | ENZYMATIC CLEAVAGE OF C-TERMINAL AMINO GROUP FROM PEPTIDE AMIDE, DEAMINATION WITH PEPTIDE AMIDASE, INCUBATION AND INOCULATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 2001-12-25 | — | — | US | disclosed |