Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CAD | P27708 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880337 | 1.00 | METAP2 (0.46) | METAP2METAP1PPIDCA12CA9 | |
| SCHEMBL8430244 | 1.00 | METAP2 (0.46) | METAP2METAP1PPIDCA12CA9 | |
| SCHEMBL4957200 | 0.85 | ALDH1A1 (0.49) | METAP2METAP1CTSSCTSKALDH1A1 | |
| SCHEMBL4957204 | 0.85 | ALDH1A1 (0.49) | METAP2METAP1CTSSCTSKALDH1A1 | |
| SCHEMBL7876246 | 0.85 | CTSS (0.43) | CA12CA9L3MBTL1CTSSCTSK | |
| SCHEMBL7878136 | 0.85 | CTSS (0.43) | CA12CA9L3MBTL1CTSSCTSK | |
| Water SCHEMBL27588204 | 0.84 | ALDH1A1 (0.48) | METAP2METAP1CTSSCTSKALDH1A1 | |
| Hydrochloric Acid SCHEMBL27865037 | 0.84 | ALDH1A1 (0.48) | METAP2METAP1CTSSCTSKALDH1A1 | |
| SCHEMBL14771644 | 0.83 | METAP2 (0.45) | METAP2METAP1PPIDL3MBTL1CTSS | |
| SCHEMBL6623780 | 0.79 | CTSK (0.63) | CTSSCTSKALDH1A1TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333176-B1 | ENZYMATIC CLEAVAGE OF C-TERMINAL AMINO GROUP FROM PEPTIDE AMIDE, DEAMINATION WITH PEPTIDE AMIDASE, INCUBATION AND INOCULATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 2001-12-25 | — | — | US | disclosed |
| US-5985632-A | Peptide amidase from xanthomonas | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-11-16 | — | — | US | disclosed |