Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878414 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4ENPSR1GAA | |
| SCHEMBL7882894 | 0.89 | TRPA1 (0.61) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL7882893 | 0.89 | TRPA1 (0.61) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL7876451 | 0.80 | RARA (0.54) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL7876455 | 0.80 | RARA (0.54) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL14227305 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ENPSR1GAA | |
| SCHEMBL28052110 | 0.79 | MMP1 (0.72) | ALDH1A1HPGDKDM4ENPSR1GAA | |
| SCHEMBL28609663 | 0.78 | SMN1; SMN2 (0.74) | ALDH1A1HPGDKDM4ENPSR1GAA | |
| SCHEMBL28609662 | 0.78 | SMN1; SMN2 (0.74) | ALDH1A1HPGDKDM4ENPSR1GAA | |
| SCHEMBL9973827 | 0.78 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ENPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |