Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | QPCT | Q16769 | 9/20 | 0.48 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877322 | 0.87 | SMN1; SMN2 (0.43) | QPCTPOLBMAPK1HTTSMN1; SMN2 | |
| SCHEMBL7879619 | 0.86 | SMN1; SMN2 (0.46) | QPCTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL7877020 | 0.86 | MAPK1 (0.46) | POLBMAPK1HTTSMN1; SMN2 | |
| SCHEMBL7875135 | 0.83 | QPCT (0.46) | CYP19A1QPCTQPCTLPOLB | |
| SCHEMBL9021654 | 0.82 | MAPK1 (0.43) | POLBMAPK1HTTSMN1; SMN2 | |
| SCHEMBL7877316 | 0.82 | SMN1; SMN2 (0.44) | POLBMAPK1HTTSMN1; SMN2 | |
| SCHEMBL8949449 | 0.74 | ALDH1A1 (0.56) | CYP19A1QPCTPOLBSMN1; SMN2 | |
| SCHEMBL8447205 | 0.74 | SOD1 (0.54) | CYP19A1QPCTPOLBSMN1; SMN2 | |
| SCHEMBL9021117 | 0.74 | MEN1 (0.46) | CYP19A1QPCTQPCTLPOLBSMN1; SMN2 | |
| SCHEMBL7879552 | 0.74 | CYP19A1 (0.64) | CYP19A1QPCTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5780642-A | NON-STEROIDAL ANTIINFLAMMATORY AGENT WHICH BLOCKS RELEASE OF ARACHIDONIC ACID FROM PHOSPHOLIPIDS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |