Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | CASP7 | P55210 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
| ▸ | CASP4 | P49662 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 2/20 | 0.40 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878944 | 0.87 | CTSL (0.52) | CTSLCTSKCTSSCASP3CASP7 | |
| SCHEMBL7885844 | 0.82 | CASP3 (0.54) | CTSLCTSKCTSSCASP3CASP7 | |
| SCHEMBL7888466 | 0.82 | CASP3 (0.52) | CTSLCTSKCTSSCASP3CASP7 | |
| SCHEMBL19015914 | 0.82 | CASP3 (0.52) | CTSLCTSKCTSSCASP3CASP7 | |
| SCHEMBL19015807 | 0.81 | CTSL (0.53) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7971579 | 0.81 | CTSL (0.51) | CTSLCTSKABCB1CASP3CASP7 | |
| SCHEMBL7888201 | 0.80 | CTSL (0.52) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7888191 | 0.79 | CTSK (0.53) | CTSLCTSKCTSSCASP3CASP1 | |
| SCHEMBL7886440 | 0.79 | CTSK (0.52) | CTSLCTSKCTSSCASP3CASP7 | |
| SCHEMBL7886897 | 0.78 | CTSK (0.44) | CTSLCTSKCTSSCASP3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |