Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270187 | 0.82 | CCNE2 (0.41) | CES1CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL31201877 | 0.75 | TDP1 (0.52) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL4121667 | 0.75 | KDM4E (0.47) | TDP1CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL3038641 | 0.74 | CES2 (0.46) | CES1CCNE2CCNE1CDK2NPC1 | |
| SCHEMBL4115207 | 0.73 | HTR1A (0.42) | TDP1S100A4 | |
| SCHEMBL3292813 | 0.73 | BCAT1 (0.50) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL4121669 | 0.73 | CCNE2 (0.36) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL28092741 | 0.72 | PTPN11 (0.46) | ABL1CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL13294923 | 0.71 | CCNE2 (0.38) | TDP1CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL8365557 | 0.71 | FFAR1 (0.39) | TDP1KMT2AGAACCNE2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883618-B1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-6022492-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICE | HOESCHT RESEARCH & TECHNOLOGY DEUTCHLAND GMBH & CO. (DE) | 2000-02-08 | — | — | US | disclosed |
| EP-0883618-A1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997024351-A1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO.KG (DE) | 1997-07-10 | — | — | WO | disclosed |