Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251342 | 0.83 | ASIC3 (0.53) | BACE1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL1915309 | 0.83 | ASIC3 (0.53) | BACE1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL263446 | 0.79 | NPC1 (0.51) | BACE1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL29496134 | 0.79 | NPC1 (0.51) | BACE1HSP90AA1HSP90AB1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL735046 | 0.78 | CYP2A6 (0.63) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| Ammonia Solution, Strong SCHEMBL10709860 | 0.78 | NOS2 (0.60) | BACE1NPC1HPGDALDH1A1KDM4E | |
| SCHEMBL7702897 | 0.77 | BACE1 (0.57) | BACE1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL4501032 | 0.76 | BACE1 (0.49) | BACE1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL671133 | 0.75 | CYP2A6 (0.67) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL29802156 | 0.75 | CYP2A6 (0.67) | NPC1RAB9ASMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6312858-B1 | IMAGED PHOTOGRAPHIC ELEMENT COMPRISING: AT LEAST ONE IMAGED LAYER COMPRISING EITHER SILVER AND/OR THE REACTION PRODUCT OF A DEVELOPING AGENT AND A DYE-FORMING COUPLER, WHICH IMAGED LAYER IS SUPERPOSED ON A SIDE OF SAID SUPPORT | EASTMAN KODAK COMPANY | 2001-11-06 | — | — | US | claimed |