Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739354 | 0.76 | MAPT (0.35) | ACHETSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL812266 | 0.76 | CNR2 (0.38) | L3MBTL1KDM4EALDH1A1HSD11B1 | |
| SCHEMBL811891 | 0.76 | LMNA (0.43) | TSHRL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL812200 | 0.73 | ACHE (0.36) | ACHETSHRL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL7879108 | 0.73 | KCNN4 (0.42) | ACHETSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL812047 | 0.72 | ALDH1A1 (0.44) | TSHRKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL20318419 | 0.72 | ACHE (0.39) | ACHETSHRL3MBTL1TDP1KDM4E | |
| SCHEMBL25881848 | 0.71 | ACHE (0.38) | ACHETSHRL3MBTL1TDP1KDM4E | |
| SCHEMBL169124 | 0.71 | TSHR (0.47) | ACHETSHRL3MBTL1TDP1KDM4E | |
| SCHEMBL29656610 | 0.71 | TSHR (0.47) | ACHETSHRL3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2157078-B1 | Fluorine compound and fluorinating agent comprising the compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2012-03-14 | — | — | EP | claimed |
| EP-1422216-B1 | FLUORINE COMPOUND AND FLUORINATING AGENT COMPRISING THE COMPOUND | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-01-07 | — | — | EP | claimed |
| US-7297821-B2 | Fluorine compound and fluorinating agent comprising the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-11-20 | — | — | US | claimed |
| US-8063205-B2 | Method for producing 2-oxazoline analogue or 1,3-oxazine analogue | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2011-11-22 | — | — | US | disclosed |
| US-7968751-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7892518-B2 | fluorinating a specific position of a saccharide substrate selectively without affecting a protective group at a temperature within a wide range safely and easily with N, N-diethyl-alpha, alpha-difluoro(3-methyl)benzylamine a fluorinating agent under irradiation with microwave or electromagnetic wave | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-02-22 | — | — | US | disclosed |
| US-7829741-B2 | Process for producing α, α-difluoroamine | NATIONAL UNIVERSITY CORPORATION (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-2189467-A2 | Method of fluorination by microwaves | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189466-A2 | METHOD OF FLUORINATION BY MICROWAVES | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-20090281309-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090177012-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE | NATIONAL UNIVERSITY CORPORATION, HOKKAIDO UNIVERSITY (JP) | 2009-07-09 | — | — | US | disclosed |
| US-7307185-B2 | Process for producing optically active fluorochemical | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20070191631-A1 | Process for producing optically active fluorochemical | MITSUBISHI GAS CHEMICAL COMPANY (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1813596-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE | National University Corporation Hokkaido University (JP) | 2007-08-01 | — | — | EP | disclosed |
| EP-1721885-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROCHEMICAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-20060089513-A1 | Fluorine compound and fluorinating agent comprising the compound | HIDAKA TOSHIO | 2006-04-27 | — | — | US | disclosed |
| US-7019173-B2 | Fluorine compound and fluorinating agent comprising the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20060014972-A1 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1568703-A1 | METHOD OF FLUORINATION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20040073065-A1 | Fluorine compound and fluorinating agent comprising the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191631-A1 | Process for producing optically active fluorochemical | PFAS, CYP4F3, CYP3A43 | ACHE 17/4885TSHR 2000/4885L3MBTL1 4674/4885 |
| US-20060089513-A1 | Fluorine compound and fluorinating agent comprising the compound | AFF1, AFF2, RER1 | ACHE 628/4885TSHR 710/4885L3MBTL1 4406/4885 |
| US-20090281309-A1 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE | OXA1L, SULT1A1, DAO | ACHE 3232/4885TSHR 1049/4885L3MBTL1 1149/4885 |
| US-20040073065-A1 | Fluorine compound and fluorinating agent comprising the compound | AFF1, RER1, AFF2 | ACHE 1008/4885TSHR 1067/4885L3MBTL1 4588/4885 |
| US-20060014972-A1 | Method of fluorination | FUCA2, FABP2, FGB | ACHE 3090/4885TSHR 2253/4885L3MBTL1 4436/4885 |
| US-20090177012-A1 | PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE | FUCA1, FUCA2, DBH | ACHE 613/4885TSHR 452/4885L3MBTL1 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.