Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271417 | 0.93 | HMOX1 (0.50) | CYP19A1TBXAS1HMOX1QPCTMEN1 | |
| SCHEMBL7868767 | 0.88 | CYP19A1 (0.47) | CYP19A1TBXAS1HMOX1QPCTMEN1 | |
| SCHEMBL7879569 | 0.85 | QPCT (0.49) | QPCTMEN1KMT2APOLBNPC1 | |
| SCHEMBL8949449 | 0.84 | ALDH1A1 (0.56) | CYP19A1QPCTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL8949432 | 0.83 | ALDH1A1 (0.55) | CYP19A1QPCTMEN1KMT2APOLB | |
| SCHEMBL8443962 | 0.83 | LMNA (0.56) | QPCTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7877319 | 0.82 | QPCT (0.44) | QPCTMEN1KMT2APOLBNPC1 | |
| SCHEMBL13696720 | 0.82 | CYP11B1 (0.55) | CYP19A1QPCTSMN1; SMN2 | |
| SCHEMBL7873773 | 0.82 | SMN1; SMN2 (0.49) | QPCTMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7876935 | 0.82 | SMN1; SMN2 (0.56) | CYP19A1MEN1KMT2APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| WO-1995022327-A1 | USE OF 1-(ARYLALKYLAMINOALKYL) IMIDAZOLES FOR TREATING NEUROLOGICAL DAMAGE | KNOLL AG (DE) | 1995-08-24 | — | — | WO | disclosed |